BioPhotonics Lab

About Us

Mission:

To develop new approaches combining visualization, diagnostics, and therapy (theranostics) using the synergy of last achievements of photonics, acoustics and material science for biomedical applications, and to bridge a gap between biophotonic research and clinical applications together with academic and industrial partners

Technologies under development:

Special fiber (photon crystal fibers, microstructured waveguides), photonic integrated circuits (PIC), optoacoustics, THz, quantum sensors, acoustics (focused ultrasound, sonoluminescence, tweezers), nanostructured materials (contrast agent, sensors, drug delivery carriers), microfluidics, surface modification – synergy in combination

Applications (Market):

Theranostics including imaging & sensing and light-, photodynamic-,sonodynamic therapy, surgical & diagnostic endoscopy, point-of-care diagnostics and health tracker (including data processing with artificial intelligence), robotic surgery​

Spin-off company "TetraQuant"

TetraQuant is a Skolkovo startup company founded in 2019 by scientists and engineers from BioPhotonics Group, Skolkovo Institute of Science and Technology with interdisciplinary background to produce tools and equipment that they have relied on routinely and now aim to help other s cientists to make their laboratory tasks easier and with great reproducibility of results.

Opportunities for students

  • Long Term Academic Mobility: Skoltech offers Academic Mobility program, which allows students to spend up to 4 months in an international institution to conduct MSc Thesis research. A lot of students in our lab participated in this program and successfully conducted their research in top-rated universities in Europe and the USA. This resulted in multiple collaborative projects and publications.
  • Short Term Academic Mobility: Skoltech encourages students to attend Russian and International conferences and present their results. All of the expences can be reimbursed!
  • Infrostructure: students have access to modern equipment.
  • The Team: work in a friendly environment with a great multisidisciplinary team!

News

Scholarships

23.08.2023

Congratulations to Sergei Perkov and Alexey Kuzin, who recieved scholarship of the Government of the Russian Federation in priority areas and scholarship of the President of the Russian Federation in priority areas accordingly.



Master's thesis defence

15.06.2023

Four MSc students from our lab have successfully defended their Master's thesis.
Viktor Vorobev: "Microsctructured optical waveguides modified by quantum dots using layer-by-layer assembly: surface modifications and optical properties",
Olga Griaznova: "Optical and photoacoustical methods for investigation of the stability of metal-organic framework colloidal solutions"
Nikita Grishaev: "Hydrophobic colloidal monolayers: fabrication, physical properties and applications in gas sensing"
Krupamay Panda: "Combination of Photonic Integrated Circuits and Microfluidic Devices for Gas Sensing"



The Best Presentation Award at the ICKEM 2023 in Istanbul

25.03.2023

Our PhD-4 student Julijana Cvjetinovic was awarded the Best Presentation Award at the 13th International Conference on Key Engineering Materials (ICKEM 2023) in Istanbul.
Her presentation was devoted to the study of nanomechanical properties of diatoms. Congratulations to Julijana on a brilliant presentation and to the entire team that worked on the study!






People

Fellow Workers

Dmitry Gorin
Head of Lab, Professor. DSc
Alexey Yashchenok
Associate Professor, DSc
Sergei German
Research Scientist, PhD
Polina Rudakovskaya
Research Scientist, PhD

PhD Students

Maksim Mokrousov
PhD-4 student, Research Intern
Anastasiia Merdalimova
PhD-4 student
Julijana Cvjetinovic
PhD-4 student, Research Intern
Sergei Perkov
PhD-3 student, Research Intern
Stas Perevoschikov
PhD-3 student
Igor Sergeev
PhD-2 student, Research Intern
Alexey Kuzin
PhD-2 student
Valentin Vlasov
PhD-2 student
Tatiana Estifeeva
PhD-1 student
Ekaterina Moiseeva
PhD-1 student, Research Intern
Dmitrii Tsiurko
PhD-1 student
Maria Blindman
PhD-1 student
Olga Griaznova
PhD-1 student

Master Students

Altynai Sydygalieva
MSc-2 student
Anna Fomina
MSc-2 student
Daria Kozhevnikova
MSc-2 student, Research Intern
Timothy Torokhov
MSc-2 student
Daria Terentieva
MSc-1 student
Sandal Vasilev
MSc-1 student
Galina Kalinchenko
MSc-1 student
Anastasiia Ivleva
MSc-1 student
Dariia Musaeva
MSc-1 student

Volunteers

Pavel Kuzmin
BSc-3 student,
Mendeleev University
Artem Aleksandrov
BSc student,
Moscow State University
Alina Dedkova
BSc student,
Bauman Moscow State Technical University

Alumni



Conferences



Recently published articles:

  1. Daria Kozhevnikova, Vasiliy Chernyshev, and Alexey Yashchenok,
    Progress in Isolation and Molecular Profiling of Small Extracellular Vesicles via Bead-Assisted Platforms.
    Biosensors, 2023, 13, 688, DOI: https://doi.org/10.3390/bios13070688, (IF=5.4, Q1)

  2. Vasiliy S. Chernyshev, Alexey Yashchenok, Mikhail Ivanov, and Denis N. Silachev,
    Filtration-based technologies for isolation, purification and analysis of extracellular vesicles.
    Phys. Chem. Chem. Phys., 2023, DOI: https://doi.org/10.1039/D3CP03129B, (IF=3.3, Q1)

  3. Mariia S. Saveleva, Mikhail E. Lobanov, Olga I. Gusliakova, Valentina O. Plastun, Ekaterina S. Prikhozhdenko, Olga A. Sindeeva, Dmitry A. Gorin, Oksana A. Mayorova,
    Mucoadhesive Emulsion Microgels for Intravesical Drug Delivery: Preparation, Retention at Urothelium, and Biodistribution Study.
    ACS Applied Materials & Interfaces, 2023, 15, 21, 25354–25368 DOI: https://doi.org/10.1021/acsami.3c02741 (IF = 9.441, Q1)

  4. Maxim A. Kurochkin, Olga A. Sindeeva, Arkady S. Abdurashitov, Nikolay A. Pyataev, Dmitry A. Gorin, Gleb B. Sukhorukov,
    In Vivo Laser-Induced Vasoactive Microenvironmental Setting via a Stimuli-Responsive Microstructured Depot.
    Biomacromolecules 2023, 24, 7, 3051–3060; https://doi.org/10.1021/acs.biomac.3c00125,(IF=6.978, Q1)

  5. Elizaveta A. Maksimova, Daniil Nozdriukhin, Sandeep Kumar Kalva, Shuxin Lyu, Berkan Lafci, Mark-Aurel Augath, Polina G. Rudakovskaya, Alexander A. Solovev, Yongfeng Mei, Xosé Luís Deán-Ben, Daniel Razansky, and Dmitry A. Gorin
    Multilayer Polymer Shell Perfluoropentane Nanodroplets for Multimodal Ultrasound, Magnetic Resonance, and Optoacoustic Imaging.
    Laser Photonics Rev 2023, 2300137, DOI: 10.1002/lpor.202300137, (IF=11, Q1)

  6. Perkov, S., Makhortov, M., Grishin, O., Perevoschikov, S., Prikhozhdenko, E. S., Bratashov, D., Gorin, D.
    Optoacoustic monitoring of bilirubin photodegradation,
    Journal of Biophotonics, 2023, e202200339, (IF=3.4, Q1)

  7. J. Cvjetinovic, S. Y. Luchkin, E.S. Statnik, N. A. Davidovich, P.A. Somov, A.I. Salimon, A.M. Korsunsky, D.A. Gorin,
    Revealing the static and dynamic nanomechanical properties of diatom frustules—Nature’s glass lace.
    Scientific Reports, 2023, 13(1), 5518, https://doi.org/10.1038/s41598-023-31487-x, (IF=4.996, Q1)



Projects

  1. Photoactivatable nanocomposite systems for MRI-guided minimally invasive glioblastoma therapy
    Project team:
    Skoltech: Prof. Dmitry Gorin, Dr. Sergey German, Julijna Cvjetinovic, Ekaterina Moiseeva, Maksim Mokrousov, Igor Sergreev
    ITMO: Prof. Anna Orlova, Dr. Viktor Zakharov, Ilia Vovk, Tonya Dadadzhanova, Maxim Rider, Ekaterina Smirnova, Konstantin Baranov, Tatiana Oskolkova
    MIPT: Dr. Sergey Novikov, Dr. Ilya Zavidovsky, Mikhail Tatmyshevskiy

  2. The use of polymers and their chemical modification for the isolation and identification of subpopulations of extracellular vesicles directed towards potential medical diagnostics and therapy
    Project team: Vasiliy Chernyshev, Ivanov M.E., Yashchenok A.M., Rudakovskaya P.G., Estifeeva T.M., Poltavtseva R.A., Svirshchevskaya E.V., Altynbaev L.A., Moiseeva E.O., Kozhevnikova D.D.

  3. Functional magnetic beads for isolation of extracellular vesicles and evaluation of their pathological capacity
    Project team: Alexey Yashchenok, Chernyshev V.S., Tryakin A.A., Kuznetsova O.A., Chuprov-Netochin R.N., Moiseeva E.O., Blindman M.A, Grishaev N.A., Kozhevnikova D.D.

  4. Bioactive ultrasound-driven microbubbles for theranostics
    Project team: Gorin D.A., Yashchenok A.M., Chernyshov V.S., German S.V., Sindeeva O.A., Rudakovskaya P.G., Maximova E.A., Gusljkova O.I, Prikhozhdenko E.S.

  5. Noninvasive optical sensing for personalized treatment of hemangioma
    Project Team: Dmitry Gorin, Sergei Pekov, Viktor Vorobev, Sergey German, Sergey Gorodkov

  6. Optical methods for monitoring the growth of the diatom algae and their activity in the carbon dioxide capturing
    Project Team: Dmitry Gorin, Alexander Korsunsky, Yekaterina Bedoshvili, Nickolai Davidovich, Sergey German, Sergey Luchkin, Julijana Cvjetinovic, Sergei Perkov, Yulia Zakharova, Elvira Bairamova

  7. New functional agents of hybrid imaging based on amphiphilic polymers for the tasks of reproductive medicine
    Project Team: Polina Rudakovskaya, Roman Barmin, Liza Maksimova, Roman Chuprov-Netochin

  8. Photoacoustic technologies for early theranostics of metastatic tumors
    Project Team: Dmitry Gorin, A.Yashchenok, M. Novoselova, S. German, M. Mokrousov, D.Nozdriukhin



Equipment

Laser Analyzer Zetasizer Nano ZS
Flow Cytometry System CytoFLEX B5-R3-V5
Operetta High Content Imaging System
IVIS Spectrum CT In Vivo Imaging System
Optoacoustic microscopy RSOM Explorer P50

Partners

Industrial Partners

Academic Partners

Contacts

Address

Rooms 120, 103.1, 044
Skolkovo Institute of Science and Technology,
Skolkovo Innovation Center, Nobel st, Building 3,
Moscow 121205,
Russia

How to find us?

On a subway train: reach "Skolkovo" station of Moscow Central Diameter D1, then take bus Sk1 to "Tatneft".
On a bus: from "Slavyanskiy bulvar" subway station take Sk express (bus) to "Tatneft".

Head of Lab

Prof. Dmitry Gorin
D.Gorin@skoltech.ru

Website administrator

Sergei Perkov
sergey.perkov97@gmail.com