To develop new approaches combining visualization, diagnostics, and therapy (theranostics) using the synergy of last achievements of photonics, acoustics and material science for biomedical applications, and to bridge a gap between biophotonic research and clinical applications together with academic and industrial partners
Special fiber (photon crystal fibers, microstructured waveguides), photonic integrated circuits (PIC), optoacoustics, THz, quantum sensors, acoustics (focused ultrasound, sonoluminescence, tweezers), nanostructured materials (contrast agent, sensors, drug delivery carriers), microfluidics, surface modification – synergy in combination
Theranostics including imaging & sensing and light-, photodynamic-,sonodynamic therapy, surgical & diagnostic endoscopy, point-of-care diagnostics and health tracker (including data processing with artificial intelligence), robotic surgery
Weekly laboratory seminar was organized. Our second year PhD student Sergei Perkov talked about his previous work and recent findings in his research.
Regular laboratory seminar was organized. Our new PhD student Aleksei Kuzin and MEPhI Bachelor student Sofia Samokhvalova, who has recently joined our group, talked about their scientific background and research plans in the laboratory.
Congratulations to Timur Ermatov for an impeccable thesis defense!
Thesis title: "Optical properties of hollow-core microstructured fibers modified by polymers and/or inorganic nano- and submicron particles".
Julijana Cvjetinovic, Anastasiia A. Merdalimova, Maria A. Kirsanova, Pavel A. Somov, Daniil V. Nozdriukhin, Alexey I. Salimon, Alexander M. Korsunsky and Dmitry A. Gorin, A SERS platform based on diatomite modified by gold nanoparticles using a combination of layer-by-layer assembly and a freezing-induced loading method. Phys. Chem. Chem. Phys., 2022,24, 8901-8912
E.S. Vavaev, M. Novoselova, N.M. Shchelkunov, S. German, A.S. Komlev, M. D. Mokrousov, I. V. Zelepukin, A. M. Burov, B. N. Khlebtsov, E. V. Lyubin, S. Deyev, A. A. Fedyanin, D.A. Gorin, CaCO3 Nanoparticles Coated with Alternating Layers of Poly-L-Arginine Hydrochloride and Fe3O4 Nanoparticles as Navigable Drug Carriers and Hyperthermia Agent, ACS Applied Nano Materials, 2022 5 (2), 2994-3006, DOI: 10.1021/acsanm.2c00338, (IF=5.097, Q2)
M. Slyusarenko, S. Shalaev, A. Valitova, L. Zabegina, N. Nikiforova, I. Nazarova, P. Rudakovskaya, M. Vorobiev, A. Lezov, L. Filatova, N. Yevlampieva, D. Gorin, P. Krzhivitsky, A. Malek, AuNP Aptasensor for Hodgkin Lymphoma Monitoring, Biosensors, 2022, 12, 23. https://doi.org/10.3390/bios12010023 (IF=5.519, Q1)
A.A. Merdalimova, P.G. Rudakovskaya, T.I. Ermatov, A.S. Smirnov, S.S. Kosolobov, J.S.Skibina, P.A. Demina, B.N. Khlebtsov, A.M. Yashchenok, D.A. Gorin, SERS Platform Based on Hollow-Core Microstructured Optical Fiber: Technology of UV-Mediated Gold Nanoparticle Growth. Biosensors, 2022, 12, 19. https://doi.org/10.3390/bios12010019
N. Kaydanov, S. Perevoschikov, S.V. German, S. A. Romanov, T. Ermatov, A. A. Kozyrev, J. Cvjetinovic, A. Machnev, R.E.Noskov, S. S. Kosolobov, J. S. Skibina, A.G. Nasibulin, C. Zakian, P. G. Lagoudakis, D. A. Gorin, Optoacoustic Effect in a Hybrid Multilayered Membrane Deposited on a Hollow-Core Microstructured Optical Waveguide. ACS Photonics, 2021, 8, 11, 3346–3356
Yashchenok AM, Gusliakova OI, Konovalova EV, Novoselova MV, Shipunova VO, Abakumova TO, Efimova OI, Kholodenko R, Schulga AA, Zatsepin TS, Gorin DA, Deyev SM. Barnase encapsulation into submicron porous CaCO3 particles: studies of loading and enzyme activity. J Mater Chem B, 2021 Oct 11. doi: 10.1039/d1tb01315g
New functional agents of hybrid imaging based on amphiphilic
polymers for the tasks of reproductive medicine
Project Team: Polina Rudakovskaya, Roman Barmin, Liza Maksimova, Roman Chuprov-Netochin
The development of multifunctional
particles for targeted stimuli-responsive therapy and diagnostics of prostate cancer
Project Team: Gorin D., Novoselova M.V., German S.V., Perevoschikov S.V. and others
Bioactive ultrasound-driven microbubbles for theranostics
Project Team: Gorin D., Yashchenok A.M., Novoselova M.V., German S.V., Rudakovskaya P.G., Gusliakova O.I. and others
Microstructured optical waveguides for the concentrations and refractive index measurements of the proteins
Project Team: Timur Ermatov
Comprehensive physical-chemical method for localizing of therapeutic agents within the target lymph node using magnetic control systems and submicron carriers
Project Team: Maxim Kurochkin
Development of multimodal contrast agents for diagnostics of sentinel lymph nodes
Project Team: Novoselova M.N., German S.V., Kurochkin M.A., Efimova O. and others.
Investigation of the effect of membrane macromolecules of extracellular nanovesicles on their surface activity and adsorption to interfaces
Project Team: Vasiliy Chernyshev
A new approach for the treatment of viral infections of the respiratory tract, including SARS-CoV-2, based on targeted delivery of vaterite particles with encapsulated ribonuclease
Project Team: Alexey Yashchenok, Abakumova T.O., Rudakovskaya P.G., Konovalova E.V. and others.
Photoacoustic technologies for early theranostics of metastatic tumors
Project Team: Dmitry Gorin, A.Yashchenok, M. Novoselova, S. German, M. Mokrousov, D.Nozdriukhin
Rooms 111, 044
Skolkovo Institute of Science and Technology,
Skolkovo Innovation Center, Nobel st, Building 3,
On a subway train: reach "Skolkovo" station of Moscow Central Diameter D1, then take minibus №1.
On a bus: from "Slavyanskiy bulvar" subway station take Sk express (bus), then change at "Technopark" station to minibus №3 or minibus №5.
Prof. Dmitry Gorin