To develop new approaches combining visualization, diagnostics, and therapy (theranostics) using the synergy of last achievements of photonics, acoustics and material science for biomedical applications, and to bridge a gap between biophotonic research and clinical applications together with academic and industrial partners
Special fiber (photon crystal fibers, microstructured waveguides), photonic integrated circuits (PIC), optoacoustics, THz, quantum sensors, acoustics (focused ultrasound, sonoluminescence, tweezers), nanostructured materials (contrast agent, sensors, drug delivery carriers), microfluidics, surface modification – synergy in combination
Theranostics including imaging & sensing and light-, photodynamic-,sonodynamic therapy, surgical & diagnostic endoscopy, point-of-care diagnostics and health tracker (including data processing with artificial intelligence), robotic surgery
Roman Barmin and Igor Sergeev have successfully defended their Master's theses.
Roman's thesis entitled "Contrast agents based on gas bubbles for photoacoustic and ultrasound-driven applications" and Igor's thesis entitled "Influence of photodynamic effect with the presence of inorganic nanoparticles on cell viability" both were graded as "A".
E.A. Maksimova , R.A. Barmin, P.G. Rudakovskaya, O.A. Sindeeva, E.S. Prikhozhdenko; A.M. Yashchenok, B.N. Khlebtsov, A.A. Solovev, G. Huang, Y. Mei, Kanti Dey, D.A. Gorin Air-Filled Microbubbles Based on Albumin Functionalized with Gold Nanocages and Zinc Phthalocyanine for Multimodal Imaging. Micromachines 2021, 12, 1161. https://doi.org/10.3390/mi12101161
Timur Ermatov, Ivan Gnusov, Julia Skibina, Roman E. Noskov, and Dmitry Gorin, Noncontact characterization of microstructured optical fibers coating in real time, Opt. Lett. 46, 4793-4796 (2021), https://doi.org/10.1364/OL.433208
Timur Ermatov, Marina Novoselova, Julia Skibina, Andrey Machnev, Dmitry Gorin, and Roman E. Noskov, Ultrasmooth, biocompatible, and removable nanocoating for hollow-core microstructured optical fibers, Opt. Lett. 46, 4828-4831 (2021)б https://doi.org/10.1364/OL.436220
R. E. Noskov, A. Machnev, I.I. Shishkin, M. V. Novoselova, A.V. Gayer, A. A. Ezhov, E. A. Shirshin, S. V. German, I.D. Rukhlenko, S. Fleming, B. N. Khlebtsov, D. A. Gorin, P. Ginzburg, Golden Vaterite as a Mesoscopic Metamaterial for Biophotonic Applications, Advanced Materials 2021, 2008484, https://doi.org/10.1002/adma.202008484, (IF=27.398, Q1, Nature Indexing Journal)
M.D. Mokrousov, W. Thompson, S.A. Ermilov, T. Abakumova, M.V. Novoselova, O. A. Inozemtseva, T. S. Zatsepin, V. P. Zharov, E.I. Galanzha, D. A. Gorin, (2021). Indocyanine green dye based bimodal contrast agent tested by photoacoustic/fluorescence tomography setup. Biomedical Optics Express, 12(6), 3181-3195, https://doi.org/10.1364/BOE.419461 (IF=3.921, Q1)
J. Mujtaba, J. Liu, K. K. Dey, T. Li, R. Chakraborty, K. Xu, D. Makarov, R.A. Barmin, D.A. Gorin, V. Tolstoy, G. S. Huang, A. A. Solovev and Y. F. Mei. Micro-Bio-Chemo-Mechanical-Systems: Micromotors, Nanozymes, and Microfluidics for Biomedical Applications. Advanced Materials, 2021, 2007456(1-40), (2021), doi.org/10.1002/adma.202007465, (IF=27.398, Q1, Nature Indexing Journal)
New functional agents of hybrid imaging based on amphiphilic
polymers for the tasks of reproductive medicine
Project Team: Polina Rudakovskaya, Roman Barmin, Liza Maksimova, Roman Chuprov-Netochin
The development of a device for hematomas and inflammations phototherapy
Project Team: Sergei Perkov, Kirill Malakhov
The development of multifunctional
particles for targeted stimuli-responsive therapy and diagnostics of prostate cancer
Project Team: Gorin D., Novoselova M.V., German S.V., Perevoschikov S.V. and others
Bioactive ultrasound-driven microbubbles for theranostics
Project Team: Gorin D., Yashchenok A.M., Novoselova M.V., German S.V., Rudakovskaya P.G., Gusliakova O.I. and others
Microstructured optical waveguides for the concentrations and refractive index measurements of the proteins
Project Team: Timur Ermatov
Comprehensive physical-chemical method for localizing of therapeutic agents within the target lymph node using magnetic control systems and submicron carriers
Project Team: Maxim Kurochkin
Investigation of the effect of membrane macromolecules of extracellular nanovesicles on their surface activity and adsorption to interfaces
Project Team: Vasiliy Chernyshev
A new approach for the treatment of viral infections of the respiratory tract, including SARS-CoV-2, based on targeted delivery of vaterite particles with encapsulated ribonuclease
Project Team: Alexey Yashchenok, Abakumova T.O., Rudakovskaya P.G., Konovalova E.V. and others.
Photoacoustic technologies for early theranostics of metastatic tumors
Project Team: Dmitry Gorin, A.Yashchenok, M. Novoselova, S. German, M. Mokrousov, D.Nozdriukhin
Rooms 111, 044
Skolkovo Institute of Science and Technology,
Skolkovo Innovation Center, Nobel st, Building 3,
On a subway train: reach "Skolkovo" station of Moscow Central Diameter D1, then take minibus №1.
On a bus: from "Slavyanskiy bulvar" subway station take Sk express (bus), then change at "Technopark" station to minibus №3 or minibus №5.
Prof. Dmitry Gorin