To develop new approaches combining visualization, diagnostics, and therapy (theranostics) using the synergy of last achievements of photonics, acoustics and material science for biomedical applications, and to bridge a gap between biophotonic research and clinical applications together with academic and industrial partners
Special fiber (photon crystal fibers, microstructured waveguides), photonic integrated circuits (PIC), optoacoustics, THz, quantum sensors, acoustics (focused ultrasound, sonoluminescence, tweezers), nanostructured materials (contrast agent, sensors, drug delivery carriers), microfluidics, surface modification – synergy in combination
Theranostics including imaging & sensing and light-, photodynamic-,sonodynamic therapy, surgical & diagnostic endoscopy, point-of-care diagnostics and health tracker (including data processing with artificial intelligence), robotic surgery
D.Nozdriukhin, N.Besedina, V.Chernyshev, O.Efimova, P. Rudakovskaya, M. Novoselova, D. Bratashov, R. Chuprov-Netochin, R. Kamyshinsky, A. Vasiliev, D. Chermoshentseva, S.A. Dyakov, V. Zharov, N. Gippius, D. A. Gorin, A. Yashchenok, Gold Nanoparticle-Carbon Nanotube Multilayers on Silica Microspheres: Optoacoustic-Raman Enhancement and Potential Biomedical applications, Materials Science and Engineering: C, Volume 120, 2021, 111736. (IF=5.88, Q1), doi.org/10.1016/j.msec.2020.111736
R.A. Barmin, P.G. Rudakovskaya, V.S. Chernyshev, O.I. Gusliakova, P.A. Belcov, E. N. Obukhova, A.V. Gayer, E. A. Shirshin, D. A. Gorin, Optoacoustic/fluorescent/acoustic imaging probe based on air-filled bubbles functionalized with gold nanorods and fluorescein isothiocyanate, ACS Omega, doi: 10.1021/acsomega.0c05518, (IF=2.87, Q2)
M.V. Novoselova, S.V. German, T.O. Abakumova, S.V. Perevoschikov, O.V. Sergeeva, M.V. Nesterchuk, O.I. Efimova, K.S. Petrov, V.S. Chernyshev, T.S. Zatsepin, D.A. Gorin, Multifunctional nanostructured drug delivery carriers for cancer therapy: multimodal imaging and ultrasound-induced drug release, Colloids and Surfaces B: Biointerfaces, 2021, 111576. doi.org/10.1016/j.colsurfb.2021.111576 (IF=4.389, Q1)
S.V. German, G.S. Budylin, E. A. Shirshin, D. A. Gorin, Advanced Technique for In Situ Raman Spectroscopy Monitoring of the Freezing-Induced Loading Process, Langmuir, https://doi.org/10.1021/acs.langmuir.0c02593 (IF=3.557, Q1)
E.S. Prikhozhdenko, O.I. Gusliakova, O.A. Kulikov, O.A. Mayorova, N.A. Shushunova, A. S. Abdurashitov , D.N. Bratashov, N.A. Pyataev, V.V. Tuchin, D.A. Gorin, G.B. Sukhorukov, O. A. Sindeeva, Target delivery of drug carriers in mice kidney glomeruli via renal artery. Balance between efficiency and safety, Journal of Controlled Release, 329 (2021) 175–190, https://doi.org/10.1016/j.jconrel.2020.11.051 (IF=7.727, Q1)
S.A. Perkov, D.A. Gorin, R.O. Esenaliev, Optoacoustic monitoring of water content in tissue phantoms and human skin, J. Biophotonics. 2020;e202000363 (IF=3.032, Q2) https://doi.org/10. 1002/jbio.202000363
T. Ermatov, R. E. Noskov, A. A. Machnev, I. Gnusov, V.Аtkin, E.N. Lazareva, S.V. German, S. S. Kosolobov, T. S. Zatsepin, O.V. Sergeeva, J.S. Skibina, P. Ginzburg, V.V. Tuchin, P. G. Lagoudakis, D. A. Gorin, Multispectral sensing of biological liquids with hollow-core microstructured optical fibres , Light: Science & Applications, 2020, 9, 173, https://doi.org/10.1038/s41377-020-00410-8 (IF= 13.714, Q1)
1. The development of multifunctional
particles for targeted stimuli-responsive therapy and diagnostics of prostate cancer
Project Team: Gorin D., Novoselova M.V., German S.V., Perevoschikov S.V. and others
2. Bioactive ultrasound-driven microbubbles for theranostics
Project Team: Gorin D., Yashchenok A.M., Novoselova M.V., German S.V., Rudakovskaya P.G., Gusliakova O.I. and others
3. Microstructured optical waveguides for the concentrations and refractive index measurements of the proteins
Project Team: Timur Ermatov
4. Comprehensive physical-chemical method for localizing of therapeutic agents within the target lymph node using magnetic control systems and submicron carriers
Project Team: Maxim Kurochkin
5. Investigation of the effect of membrane macromolecules of extracellular nanovesicles on their surface activity and adsorption to interfaces
Project Team: Vasiliy Chernyshev
6. A new approach for the treatment of viral infections of the respiratory tract, including SARS-CoV-2, based on targeted delivery of vaterite particles with encapsulated ribonuclease
Project Team: Alexey Yashchenok, Abakumova T.O., Rudakovskaya P.G., Konovalova E.V. and others.
7. Photoacoustic technologies for early theranostics of metastatic tumors
Project Team: Dmitry Gorin, A.Yashchenok, M. Novoselova, S. German, M. Mokrousov, D.Nozdriukhin
Rooms 241, 044
Skolkovo Institute of Science and Technology,
Skolkovo Innovation Center, Nobel st, Building 3,
Moscow 121205,
Russia
On a subway train: reach "Skolkovo" station of Moscow Central Diameter D1, then take minibus №1.
On a bus: from "Slavyanskiy bulvar" subway station take Sk express (bus), then change at "Technopark" station to minibus №3 or minibus №5.
Prof. Dmitry Gorin
D.Gorin@skoltech.ru
Sergei Perkov
sergey.perkov97@gmail.com
