BioPhotonics Lab

About Us

Mission:

To develop new approaches combining visualization, diagnostics, and therapy (theranostics) using the synergy of last achievements of photonics, acoustics and material science for biomedical applications, and to bridge a gap between biophotonic research and clinical applications together with academic and industrial partners

Technologies under development:

Special fiber (photon crystal fibers, microstructured waveguides), photonic integrated circuits (PIC), optoacoustics, THz, quantum sensors, acoustics (focused ultrasound, sonoluminescence, tweezers), nanostructured materials (contrast agent, sensors, drug delivery carriers), microfluidics, surface modification – synergy in combination

Applications (Market):

Theranostics including imaging & sensing and light-, photodynamic-,sonodynamic therapy, surgical & diagnostic endoscopy, point-of-care diagnostics and health tracker (including data processing with artificial intelligence), robotic surgery​

Spin-off company "TetraQuant"

TetraQuant is a Skolkovo startup company founded in 2019 by scientists and engineers from BioPhotonics Group, Skolkovo Institute of Science and Technology with interdisciplinary background to produce tools and equipment that they have relied on routinely and now aim to help other scientists to make their laboratory tasks easier and with great reproducibility of results.

Opportunities for students

  • Long Term Academic Mobility: Skoltech offers Academic Mobility program, which allows students to spend up to 4 months in an international institution to conduct MSc Thesis research. A lot of students in our lab participated in this program and successfully conducted their research in top-rated universities in Europe and the USA. This resulted in multiple collaborative projects and publications.
  • Short Term Academic Mobility: Skoltech encourages students to attend Russian and International conferences and present their results. All of the expences can be reimbursed!
  • Infrostructure: students have access to modern equipment.
  • The Team: work in a friendly environment with a great multisidisciplinary team!

News

Scholarships

21.06.2024

Congratulations to Alexey Kuzin, who received Scholarship of the President of the Russian Federation for PhD students conducting scientific research within the framework of implementation of the priorities of scientific and technological development of the Russian Federation, defined in the strategy of scientific and technological development of the Russian Federation.



Master's thesis defence

11.06.2024

Four MSc students from our lab have successfully defended their Master's thesis.
Altynai Sydygalieva: "Non–invasive optical monitoring of skin water content",
Timothy Torokhov: "Development of Skin Phantoms of Infantile Hemangioma for Multispectral Imaging"
Daria Kozhevnikova: "Development of a methodology for detecting HER2-positive extracellular vesicles in the blood plasma of breast cancer patients"
Anna Fomina: "Development of systems for targeted delivery of DNA to bipolar retinal cells for the treatment retinitis pigmentosa (RP)"



Kolba Prize for Women in Science and Technology

24.04.2024

Senior researcher Dr. Julijana Cvjetinovic became a laureate of the Kolba Prize for Women in Science and Technology!
Julijana's research focuses on studying the optical and mechanical properties of diatoms, a type of single-celled microorganisms coated in silica shells. She is also developing optical methods to monitor their growth and carbon dioxide sequestration activity. Her work could help solve fundamental problems in bionics and suggest efficient exoskeleton structures for high-performance engineering devices.
We congratulate Julijana on her remarkable achievement and wish her further success in her future endeavors!






People

Fellow Workers

Dmitry Gorin
Head of Lab, Professor. DSc
Alexey Yashchenok
Associate Professor, DSc
Sergei German
Senior Research Scientist, PhD
Polina Rudakovskaya
Research Scientist, PhD
Julijana Cvjetinovic
Senior Research Scientist, PhD
Maksim Mokrousov
Research Engineer, MSc
Daria Kozhevnikova
Research Intern, MSc

PhD Students

Sergei Perkov
PhD-4 student, Junior Research Scientist
Stas Perevoschikov
PhD-3 student (on Academic Leave)
Igor Sergeev
PhD-3 student, Research Intern
Alexey Kuzin
PhD-3 student
Valentin Vlasov
PhD-3 student
Tatiana Estifeeva
PhD-2 student, Junior Research Scientist
Ekaterina Moiseeva
PhD-2 student, Research Intern
Dmitrii Tsiurko
PhD-2 student
Maria Blindman
PhD-1 student, Research Intern
Olga Griaznova
PhD-1 student

Master Students

Daria Terentieva
MSc-1 student, Research Intern
Sandal Vasilev
MSc-1 student
Galina Kalinchenko
MSc-1 student
Anastasiia Ivleva
MSc-1 student
Dariia Musaeva
MSc-1 student
Arina Papugaeva
MSc-1 student
Mariia Reshetova
MSc-1 student

Volunteers

Pavel Kuzmin
BSc-3 student,
Mendeleev University
Artem Aleksandrov
BSc
Alina Dedkova
BSc
Altynai Sydygalieva
MSc
Anna Fomina
MSc
Timothy Torokhov
MSc
Viktoriia Galanova
MSc

Alumni



Conferences



Recently published articles:

  1. A Kuzin, K Panda, V Chernyshev, I Florya, V Kovalyuk, P An, A Golikov, G Chulkova, D Kolesov, D Gorin, G Goltsman
    Microfluidic–nanophotonic sensor for on-chip analysis of complex refractive index.
    Applied Physics Letters, 2024, 124(6), https://doi.org/10.1063/5.0190351

  2. Igor S. Sergeev, Elizaveta A. Maksimova, Ekaterina O. Moiseeva, Olga Yu. Griaznova, Sergei A. Perkov, Polina A. Demina, Valeriy D. Zaytsev, Yury A. Koksharov, Maxim A. Rider, Ilya A. Zavidovskiy, Polina G. Rudakovskaya, Roman I. Romanov, Boris N. Khlebtsov, Anna O. Orlova, Sergey M. Deyev, Dmitry A. Gorin
    Photoinduced Toxicity Caused by Gold Nanozymes and Photodynamic Dye Encapsulated in Submicron Polymer Shell.
    Particle & Particle Systems Characterization, 2024, https://doi.org/10.1002/ppsc.202300149

  3. Anastasiia Merdalimova, Roman Barmin, Viktor VorobevArtem AleksandrovDaria TerentyevaTatiana EstifeevaVasiliy ChernyshevSergey GermanOleg MaslovYulia SkibinaPolina RudakovskayaDmitry Gorin
    Two-in-One Sensor of Refractive Index and Raman Scattering using Hollow−Core Microstructured Optical Waveguides for Colloid Characterization.
    Colloids and Surfaces B: Biointerfaces, 2023, https://doi.org/10.1016/j.colsurfb.2023.113705

  4. Cvjetinovic J, Luchkin S, Perevoschikov S, Davidovich N, Salimon A, Bedoshvili Ye, Somov P, Lagoudakis P, Korsunsky A, Gorin D
    Probing vibrational eigenmodes in diatom frustules via combined in silico computational study and atomic force microscopy experimentation.
    Applied Physics Letters, 2023, 123 (18), https://doi.org/10.1063/5.0171503, (IF=3.971, Q1, SJR - 1.043, Nature Index)

  5. A. Kuzin, V. Chernyshev, V. Kovalyuk, P. An, A. Golikov, S. Svyatodukh, S. Perevoschikov, I. Florya, A. Schulga, S. Deyev, G. Goltsman, D. Gorin
    Real-time surface functionalization of a nanophotonic sensor for liquid biopsy.
    Applied Physics Letters, 2023, 123, 193702, https://doi.org/10.1063/5.0167631, (IF=3.971, Q1, SJR - 1.043, Nature Index)

  6. Statnik E, Cvjetinovic J, Ignatyev S, Wassouf L, Salimon A, Korsunsky A.
    Hair-Reinforced Elastomer Matrix Composites: Formulation, Mechanical Testing, and Advanced Microstructural Characterization.
    Polymers, 2023, 15(22):4448, https://doi.org/10.3390/polym15224448.

  7. Sergei Perkov, Viktor Vorobev, Maxim A Kurochkin, Sergey Gorodkov, Dmitry Gorin
    Rapid low‐cost hyperspectral imaging system for quantitative assessment of infantile hemangioma.
    Journal of Biophotonics, 2023, e202300375, https://doi.org/10.1002/jbio.202300375, (IF=3.4, Q1)



Recently published patents

  1. Sergei PerkovViktor VorobevDmitry Gorin
    Hyperspectral hematoma analyzer
    Patent No: 2805769, Registration date: 24.10.2023, Application No: 2023114467 from 01.06.2023

  2. A. YaschenokV. ChernyshevS. German, A. Shulga, S. Deev, D. Gorin, E. Konovalova
    Method for exoaomes extraction and analysis
    Patent No: RU 2788198 C1, Registration date: 17.01.2023, Application No: 2022102303 from 25.03.2022

  3. S. GermanD. GorinD. Rahmanov, A. Yaschenok
    Automated chemical reactor
    Patent No: RU 2788262 C1, Registration date: 17.01.2023, Application No: 2022127227 from 20.10.2022



Projects

  1. Noninvasive optical sensing for personalized treatment of hemangioma
    Project Team: Dmitry Gorin, Sergei Pekov, Viktor Vorobev, Sergey German, Sergey Gorodkov

  2. Photoactivatable nanocomposite systems for MRI-guided minimally invasive glioblastoma therapy
    Project team:
    Skoltech: Prof. Dmitry Gorin, Dr. Sergey German, Julijna Cvjetinovic, Ekaterina Moiseeva, Maksim Mokrousov, Igor Sergreev
    ITMO: Prof. Anna Orlova, Dr. Viktor Zakharov, Ilia Vovk, Tonya Dadadzhanova, Maxim Rider, Ekaterina Smirnova, Konstantin Baranov, Tatiana Oskolkova
    MIPT: Dr. Sergey Novikov, Dr. Ilya Zavidovsky, Mikhail Tatmyshevskiy

  3. The use of polymers and their chemical modification for the isolation and identification of subpopulations of extracellular vesicles directed towards potential medical diagnostics and therapy
    Project team: Vasiliy Chernyshev, Ivanov M.E., Yashchenok A.M., Rudakovskaya P.G., Estifeeva T.M., Poltavtseva R.A., Svirshchevskaya E.V., Altynbaev L.A., Moiseeva E.O., Kozhevnikova D.D.

  4. Functional magnetic beads for isolation of extracellular vesicles and evaluation of their pathological capacity
    Project team: Alexey Yashchenok, Chernyshev V.S., Tryakin A.A., Kuznetsova O.A., Chuprov-Netochin R.N., Moiseeva E.O., Blindman M.A, Grishaev N.A., Kozhevnikova D.D.

  5. Optical methods for monitoring the growth of the diatom algae and their activity in the carbon dioxide capturing
    Project Team: Dmitry Gorin, Alexander Korsunsky, Yekaterina Bedoshvili, Nickolai Davidovich, Sergey German, Sergey Luchkin, Julijana Cvjetinovic, Sergei Perkov, Yulia Zakharova, Elvira Bairamova

  6. Photoacoustic technologies for early theranostics of metastatic tumors
    Project Team: Dmitry Gorin, A.Yashchenok, M. Novoselova, S. German, M. Mokrousov, D.Nozdriukhin



Equipment

Laser Analyzer Zetasizer Nano ZS
Flow Cytometry System CytoFLEX B5-R3-V5
Operetta High Content Imaging System
IVIS Spectrum CT In Vivo Imaging System
Optoacoustic microscopy RSOM Explorer P50

Partners

Industrial Partners

Academic Partners

Contacts

Address

Rooms 120, 103.1, 044
Skolkovo Institute of Science and Technology,
Skolkovo Innovation Center, Nobel st, Building 3,
Moscow 121205,
Russia

How to find us?

On a subway train: reach "Skolkovo" station of Moscow Central Diameter D1, then take bus Sk1 to "Tatneft".
On a bus: from "Slavyanskiy bulvar" subway station take Sk express (bus) to "Tatneft".

Head of Lab

Prof. Dmitry Gorin
D.Gorin@skoltech.ru

Website administrator

Sergei Perkov
sergey.perkov97@gmail.com