Current projects

  1. Photoactivatable nanocomposite systems for MRI-guided minimally invasive glioblastoma therapy

    Funding: Clover project

    Skoltech: PI - Prof. Dmitry Gorin
    Project team:Dr. Sergey German, Julijna Cvjetinovic, Ekaterina Moiseeva, Maksim Mokrousov, Igor Sergreev

    ITMO: PI - Prof. Anna Orlova
    Project team: Dr. Viktor Zakharov, Ilia Vovk, Tonya Dadadzhanova, Maxim Rider, Ekaterina Smirnova, Konstantin Baranov, Tatiana Oskolkova

    MIPT: PI - Dr. Sergey Novikov
    Project team: Dr. Ilya Zavidovsky, Mikhail Tatmyshevskiy

    Academic partner: Biophysics Department of Biological Faculty of MSU
    Clinical partner: Federal Center for Brain and Neurotechnology
    Industrial partner: LLC "TetraQuant"

  2. The use of polymers and their chemical modification for the isolation and identification of subpopulations of extracellular vesicles directed towards potential medical diagnostics and therapy

    Funding: RSF, Project 23-13-00035 (2023-2026, 7M Rub per year)
    PI – Vasiliy Chernyshev,
    Project team: Ivanov M.E., Yashchenok A.M., Rudakovskaya P.G., Estifeeva T.M., Poltavtseva R.A., Svirshchevskaya E.V., Altynbaev L.A., Moiseeva E.O., Kozhevnikova D.D.
    Academic partners: National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry; Alferov University

  3. Functional magnetic beads for isolation of extracellular vesicles and evaluation of their pathological capacity

    Funding: RSF, Project 23-74-00022 (2023-2026, 7M Rub per year)
    PI – Alexey Yashchenok,
    Project team: Chernyshev V.S., Tryakin A.A., Kuznetsova O.A., Chuprov-Netochin R.N., Moiseeva E.O., Blindman M.A, Grishaev N.A., Kozhevnikova D.D.
    Clinical partners: FSBI "National Medical Research Center of Oncology named after N.N. N.N. Blokhin

  4. Bioactive ultrasound-driven microbubbles for theranostics

    Funding: RFBR,  19-53-80047 БРИКC (2022 - 2023)
    PI – Dmitry Gorin,
    Project team: Yashchenok A.M., Chernyshov V.S., German S.V., Sindeeva O.A., Rudakovskaya P.G., Maximova E.A. Gusljkova O.I, Prikhozhdenko E.S.

  5. Noninvasive optical sensing for personalized treatment of hemangioma

    Funding: Internal Skoltech Project (NGP) (2022 - 2023, 6M RUB for 2022)
    PI – Gorin D.,
    Project team: German S., Perkov S., Vorobev V. and Gorodkov S.

  6. Optical methods for monitoring the growth of the diatom algae and their activity in the carbon dioxide capturing

    Funding: RSF Foundation, Project № 22-14-00209 (2022 - 2024, 6M RUB for 2022)
    PI – Gorin D.,
    Project team: Korsunsky A., German S., Cvjetinovic J., Perkov S. and others.

  7. New functional agents of hybrid imaging based on amphiphilic polymers for the tasks of reproductive medicine

    Funding: RSF Foundation, Project № 21-73-10254 (2021 - 2023, 6M RUB for 2021)
    PI – Polina Rudakovskaya,
    Project team: Barmin R., Maksimova L., Chuprov-Netochin R.

  8. Photoacoustic technologies for early theranostics of metastatic tumors

    Funding: Contract with Saratov State University (the group led by Prof. V.P. Zharov) in the frame of a program sponsored by the Government of the Russian Federation in Saratov State University, (2019 - . . ., 1M RUB per year)
    PI – Dmitry Gorin,
    Project team: A.Yashchenok, M. Novoselova, S. German, M. Mokrousov, D.Nozdriukhin

Past projects

  1. Investigation of the effect of membrane macromolecules of extracellular nanovesicles on their surface activity and adsorption to interfaces

    Funding: RSF Foundation, (2020 - 2022, 1.5M RUB per year)
    PI - Vasiliy Chernyshev

  2. Development of multimodal contrast agents for the diagnostics of sentinel lymph nodes

    Funding: RSF Foundation (2020 - 2023, 5M RUB per year)
    PI - Marina Novoselova,
    Project team: German S.V., Kurochkin M.A., Efimova O., Abalymov A., Kopnin P.B., Novikova M.V., Vorontsov D.A.
    Academic partners: N.N. Blokhin Russian Cancer Research Center; Nizhny Novgorod Regional Clinical Oncology Center

  3. Comprehensive physical-chemical method for localizing of therapeutic agents within the target lymph node using magnetic control systems and submicron carriers

    Funding: RFBR, Project 19-32-60058 (01.11.2019 - 31.10.2022, 3M RUB per year)
    PI - Maxim Kurochkin

  4. The development of a device for hematomas and inflammations phototherapy

    Funding: Russian Fund for Innovation Support, (2021 - 2023, 500k RUB)
    PI – Sergei Perkov,

  5. A new approach for the treatment of viral infections of the respiratory tract, including SARS-CoV-2, based on targeted delivery of vaterite particles with encapsulated ribonuclease

    Funding: RFBR,  20-04-60150 (2020 - 2022, 6M RUB per year)
    PI – Alexey Yashchenok,
    Project team: Abakumova T.O., Rudakovskaya P.G., Konovalova E.V., Schulga A.A., Guslyakova O.I.
    Academic partners: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry

  6. Microstructured optical waveguides for the concentrations and refractive index measurements of the proteins

    Funding: RFBR, Project 19-32-90249 (01.10.2019 - 30.09.2021, 1.2M RUB per 2 years)
    PI - Timur Ermatov

  7. The development of multifunctional particles for targeted stimuli-responsive therapy and diagnostics of prostate cancer

    Funding: RFBR, Project № 18-29-08046, (2018 - 2020, 5M RUB - 2019)
    PI – Dmitry Gorin,
    Project team: Sergeeva О.V., Novoselova M.V., Abakumova T.A., German S.V., Perevozchnokov S.V, Voronin D.V, Kozlova A.A., Nesterchuk M.V.

  8. Carrier cocktails for targeted delivery and release of biologically active substances at certain period of time

    Funding: RSF Foundation (2018 - 2019, 1.5M RUB - 2019)
    PI – Marina Novoselova,
    Academic partners: Life Science (Skoltech)

  9. An Interface of Physics and Life Sciences for Cancer Diagnostics

    Funding: Internal Skoltech Project (STRIP) (2018 - 2019, 5,428,816 RUB for two years)
    PI – Dmitry Gorin, Respinsible Researcher - Alexey Yashchenok
    Project Team: V. Chernyshev, P. Rudakovskaya, A. Malek, S. German, A. Merdalimova D.Nozdriukhin.

  10. Development of Sensor for meat spoilage recognition

    Funding: Samsung R&D Institute Rus, LLC (2019, 5.685M RUB)
    PI – Dmitry Gorin,
    Project Team: A.Yashchenok, P.Rudakovskaya, V. Chernishov, T. Ermatov, S. German, U.Bondareva, V. Shapovalov,  B. Khlebtsov  V. Belotelov, P. Kapralov, D. Ignatyeva, A.Voronov, G.Knyazev, S.Dagesyan