BioPhotonics Group

Moscow, Russia

About Us

Mission:

To develop new approaches combining visualization, diagnostics, and therapy (theranostics) using the synergy of last achievements of photonics, acoustics and material science for biomedical applications, and to bridge a gap between biophotonic research and clinical applications together with academic and industrial partners

Technologies under development:

Special fiber (photon crystal fibers, microstructured waveguides), photonic integrated circuits (PIC), optoacoustics, THz, quantum sensors, acoustics (focused ultrasound, sonoluminescence, tweezers), nanostructured materials (contrast agent, sensors, drug delivery carriers), microfluidics, surface modification – synergy in combination

Applications (Market):

Theranostics including imaging & sensing and light-, photodynamic-,sonodynamic therapy, surgical & diagnostic endoscopy, point-of-care diagnostics and health tracker (including data processing with artificial intelligence), robotic surgery​

Tasks:

  • visualization of pathology tissue and interface of normal/pathological tissues diagnostics using of modern photonics (optical fibers, PIC, optoacoustics (OA), THz, quantum sensors), acoustics, and materials science (microfluidics, surface modification, multimodal contrast agents based on nanostructured particles (US-, OA-, Fluorescent and Magnetic Resonance Imaging));

  • R&D of devices combining photonic tools (optical fibers, PIC, optoacoustics, THz) for detection of biologically important markers and drug delivery targeted systems with remote controlled by acoustic and electromagnetic fields;

  • R&D of new methods and devices for diagnostics of pathology state and transient processes from normal state to pathology and its correction on cell, tissue, and body levels (exosome detection, circulation tumor cell detection, oxygenation monitoring, etc.) using modern photonics (optical fibers, PIC, optoacoustics, THz, quantum sensors) and acoustics (focused ultrasound (US), sonoluminescence).

Spin-off company "TetraQuant"

TetraQuant is a Skolkovo startup company founded in 2019 by scientists and engineers from BioPhotonics Group, Skolkovo Institute of Science and Technology with interdisciplinary background to produce tools and equipment that they have relied on routinely and now aim to help other s cientists to make their laboratory tasks easier and with great reproducibility of results.

Opportunities for students

  • Long Term Academic Mobility: Skoltech offers Academic Mobility program, which allows students to spend up to 4 months in an international institution to conduct MSc Thesis research. A lot of students in our lab participated in this program and successfully conducted their research in top-rated universities in Europe and the USA. This resulted in multiple collaborative projects and publications.
  • Short Term Academic Mobility: Skoltech encourages students to attend Russian and International conferences and present their results. All of the expences can be reimbursed!
  • Infrostructure: students have access to modern equipment.
  • The Team: work in a friendly environment with a great multisidisciplinary team!

The Team

Fellow workers

Dmitry Gorin
Head of Lab, Professor
Alexey Yashchenok
Leading Research Scientist
Sergei German
Research Scientist
Marina Novoselova
Research Scientist
Vasiliy Chernyshev
Research Scientist
Maxim Kurochkin
Research Scientist
Polina Rudakovskaya
Research Scientist

PhD Students

Timur Ermatov
PhD-4 student, Research Intern
Maksim Mokrousov
PhD-2 student
Anastasiia Merdalimova
PhD-2 student
Julijana Cvjetinovic
PhD-2 student
Sergei Perkov
PhD-1 student
Daniil Nozdruikhin
PhD-1 student
Stas Perevoschikov
PhD-1 student

Master Students

Igor Sergeev
MSc-2 student
Roman Barmin
MSc-2 student
Liza Maksimova
MSc-1 student
See Alumni

Recently published articles:

  1. R.A. Barmin, P.G. Rudakovskaya, O.I. Gusliakova, O.A. Sindeeva, E.S. Prikhozhdenko, E.A Maksimova, E.N. Obukhova, V.S. Chernyshev, B.N. Khlebtsov, A.A. Solovev, G.B. Sukhorukov, D.A. Gorin, Air-filled bubbles stabilized by gold nanoparticle/ photodynamic dye hybrid structures for theranostics, Nanomaterials, doi:10.3390/nano11020415 (IF=4.324, Q1)

  2. M.A. Slyusarenko, N.S. Nikiforova, E. I. Sidina, I.V. Nazarova, V.V. Egorov, Y.P. Garmay, A.A. Merdalimova, N.P. Yevlampieva, D.A. Dorin, A.V. Malek, Formation and evaluation of a two-phase polymer system in human plasma as a method for extracellular nanovesicle isolation, Polymers (Basel), 2021, 13(3):1–16, https://doi.org/10.3390/polym13030458 (IF=3.426, Q1)

  3. D.Nozdriukhin, N.Besedina, V.Chernyshev, O.Efimova, P. Rudakovskaya, M. Novoselova, D. Bratashov, R. Chuprov-Netochin, R. Kamyshinsky, A. Vasiliev, D. Chermoshentseva, S.A. Dyakov, V. Zharov, N. Gippius, D. A. Gorin, A. Yashchenok, Gold Nanoparticle-Carbon Nanotube Multilayers on Silica Microspheres: Optoacoustic-Raman Enhancement and Potential Biomedical applications, Materials Science and Engineering: C, Volume 120, 2021, 111736. (IF=5.88, Q1), doi.org/10.1016/j.msec.2020.111736

  4. R.A. Barmin, P.G. Rudakovskaya, V.S. Chernyshev, O.I. Gusliakova, P.A. Belcov, E. N. Obukhova, A.V. Gayer, E. A. Shirshin, D. A. Gorin, Optoacoustic/fluorescent/acoustic imaging probe based on air-filled bubbles functionalized with gold nanorods and fluorescein isothiocyanate, ACS Omega, doi: 10.1021/acsomega.0c05518, (IF=2.87, Q2)

  5. M.V. Novoselova, S.V. German, T.O. Abakumova, S.V. Perevoschikov, O.V. Sergeeva, M.V. Nesterchuk, O.I. Efimova, K.S. Petrov, V.S. Chernyshev, T.S. Zatsepin, D.A. Gorin, Multifunctional nanostructured drug delivery carriers for cancer therapy: multimodal imaging and ultrasound-induced drug release, Colloids and Surfaces B: Biointerfaces, 2021, 111576. doi.org/10.1016/j.colsurfb.2021.111576 (IF=4.389, Q1)

  6. S.V. German, G.S. Budylin, E. A. Shirshin, D. A. Gorin, Advanced Technique for In Situ Raman Spectroscopy Monitoring of the Freezing-Induced Loading Process, Langmuir, https://doi.org/10.1021/acs.langmuir.0c02593 (IF=3.557, Q1)

Read More

Projects

1. The development of multifunctional particles for targeted stimuli-responsive therapy and diagnostics of prostate cancer
Project Team: Gorin D., Novoselova M.V., German S.V., Perevoschikov S.V. and others

2. Bioactive ultrasound-driven microbubbles for theranostics
Project Team: Gorin D., Yashchenok A.M., Novoselova M.V., German S.V., Rudakovskaya P.G., Gusliakova O.I. and others

3. Microstructured optical waveguides for the concentrations and refractive index measurements of the proteins
Project Team: Timur Ermatov

4. Comprehensive physical-chemical method for localizing of therapeutic agents within the target lymph node using magnetic control systems and submicron carriers
Project Team: Maxim Kurochkin

5. Investigation of the effect of membrane macromolecules of extracellular nanovesicles on their surface activity and adsorption to interfaces
Project Team: Vasiliy Chernyshev

6. A new approach for the treatment of viral infections of the respiratory tract, including SARS-CoV-2, based on targeted delivery of vaterite particles with encapsulated ribonuclease
Project Team: Alexey Yashchenok, Abakumova T.O., Rudakovskaya P.G., Konovalova E.V. and others.

7. Photoacoustic technologies for early theranostics of metastatic tumors
Project Team: Dmitry Gorin, A.Yashchenok, M. Novoselova, S. German, M. Mokrousov, D.Nozdriukhin

Read More

Equipment

Laser Analyzer Zetasizer Nano ZS
Flow Cytometry System CytoFLEX B5-R3-V5
Operetta High Content Imaging System
IVIS Spectrum CT In Vivo Imaging System
Optoacoustic microscopy RSOM Explorer P50

Partners

Industrial Partners

Academic Partners

Contacts

Address

Rooms 241, 044
Skolkovo Institute of Science and Technology,
Skolkovo Innovation Center, Nobel st, Building 3,
Moscow 121205,
Russia

How to find us?

On a subway train: reach "Skolkovo" station of Moscow Central Diameter D1, then take minibus №1.
On a bus: from "Slavyanskiy bulvar" subway station take Sk express (bus), then change at "Technopark" station to minibus №3 or minibus №5.

Head of Lab

Prof. Dmitry Gorin
D.Gorin@skoltech.ru

Website administrator

Sergei Perkov
sergey.perkov97@gmail.com